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Biological parameters predictive of percent dense red blood cell decrease under hydroxyurea
BACKGROUND: Dense red blood cells (DRBCs) are associated with chronic clinical manifestations of sickle-cell–disease (SCD). Hydroxyurea (HU) decreases the percent (%) DRBCs, thereby improving its therapeutic benefits, especially the prevention of SCD clinical complications, but parameters influencin...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430928/ https://www.ncbi.nlm.nih.gov/pubmed/25956133 http://dx.doi.org/10.1186/s13023-015-0272-3 |