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Biological parameters predictive of percent dense red blood cell decrease under hydroxyurea

BACKGROUND: Dense red blood cells (DRBCs) are associated with chronic clinical manifestations of sickle-cell–disease (SCD). Hydroxyurea (HU) decreases the percent (%) DRBCs, thereby improving its therapeutic benefits, especially the prevention of SCD clinical complications, but parameters influencin...

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Detalles Bibliográficos
Autores principales: Rakotoson, Marie Georgine, Di Liberto, Gaetana, Audureau, Etienne, Habibi, Anoosha, Fauroux, Christine, Khorgami, Sanam, Hulin, Anne, Loric, Sylvain, Noizat-Pirenne, France, Galacteros, Frédéric, Bartolucci, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430928/
https://www.ncbi.nlm.nih.gov/pubmed/25956133
http://dx.doi.org/10.1186/s13023-015-0272-3