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Effect of SMAD7 gene overexpression on TGF-β1-induced profibrotic responses in fibroblasts derived from Peyronie's plaque

Transforming growth factor-β1 (TGF-β1) has been identified as one of the most important fibrogenic cytokines associated with Peyronie's disease (PD). The mothers against decapentaplegic homolog 7 (SMAD7) is an inhibitory Smad protein that blocks TGF-β signaling pathway. The aim of this study wa...

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Detalles Bibliográficos
Autores principales: Choi, Min Ji, Song, Kang-Moon, Park, Jin-Mi, Kwon, Mi-Hye, Kwon, Ki-Dong, Park, Soo-Hwan, Ryu, Dong-Soo, Ryu, Ji-Kan, Suh, Jun-Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430956/
https://www.ncbi.nlm.nih.gov/pubmed/25532569
http://dx.doi.org/10.4103/1008-682X.142130