Cargando…

Effect of SMAD7 gene overexpression on TGF-β1-induced profibrotic responses in fibroblasts derived from Peyronie's plaque

Transforming growth factor-β1 (TGF-β1) has been identified as one of the most important fibrogenic cytokines associated with Peyronie's disease (PD). The mothers against decapentaplegic homolog 7 (SMAD7) is an inhibitory Smad protein that blocks TGF-β signaling pathway. The aim of this study wa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Choi, Min Ji, Song, Kang-Moon, Park, Jin-Mi, Kwon, Mi-Hye, Kwon, Ki-Dong, Park, Soo-Hwan, Ryu, Dong-Soo, Ryu, Ji-Kan, Suh, Jun-Kyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430956/ https://www.ncbi.nlm.nih.gov/pubmed/25532569 http://dx.doi.org/10.4103/1008-682X.142130

Ejemplares similares

Silencing Histone Deacetylase 7 Alleviates Transforming Growth Factor-β1-Induced Profibrotic Responses in Fibroblasts Derived from Peyronie's Plaque
por: Kang, Dong Hyuk, et al.
Publicado: (2018)

Activin Receptor-Like Kinase 5 Inhibitor Attenuates Fibrosis in Fibroblasts Derived from Peyronie's Plaque
por: Jang, Jin Hyuk, et al.
Publicado: (2012)

AB083. TEW-7197, a novel orally bioavailable activin receptor-like kinase 5 inhibitor, promotes regression of fibrotic plaque in a rat model of Peyronie’s disease
por: Song, Kang-Moon, et al.
Publicado: (2018)

The Outcome of Multiple Slit on Plaque with Plication Technique for the Treatment of Peyronie's Disease
por: Shin, Su Hwan, et al.
Publicado: (2016)

Vactosertib, a Novel, Orally Bioavailable Activin Receptor-Like Kinase 5 Inhibitor, Promotes Regression of Fibrotic Plaques in a Rat Model of Peyronie's Disease
por: Song, Kang-Moon, et al.
Publicado: (2020)

Optimizing in vivo gene transfer into mouse corpus cavernosum by use of surface electroporation
por: Song, Kang-Moon, et al.
Publicado: (2015)

RNA-sequencing profiling analysis of pericyte-derived extracellular vesicle–mimetic nanovesicles-regulated genes in primary cultured fibroblasts from normal and Peyronie’s disease penile tunica albuginea
por: Yin, Guo Nan, et al.
Publicado: (2021)

AB082. The outcome of multiple slit on plaque with plication technique for the treatment of Peyronie’s disease
por: Kang, Jae Il, et al.
Publicado: (2016)

Enhanced asthma-related fibroblast to myofibroblast transition is the result of profibrotic TGF-β/Smad2/3 pathway intensification and antifibrotic TGF-β/Smad1/5/(8)9 pathway impairment
por: Wnuk, Dawid, et al.
Publicado: (2020)

GPCR-induced YAP activation sensitizes fibroblasts to profibrotic activity of TGFβ1
por: Zmajkovicova, Katarina, et al.
Publicado: (2020)

Siglec-F–expressing neutrophils are essential for creating a profibrotic microenvironment in renal fibrosis
por: Ryu, Seungwon, et al.
Publicado: (2022)

Pomolic Acid Ameliorates Fibroblast Activation and Renal Interstitial Fibrosis through Inhibition of SMAD-STAT Signaling Pathways
por: Park, Ji-Hyun, et al.
Publicado: (2018)

Mechanical regulation of cardiac fibroblast profibrotic phenotypes
por: Herum, Kate M., et al.
Publicado: (2017)

Probiotics counteract the expression of hepatic profibrotic genes via the attenuation of TGF-β/SMAD signaling and autophagy in hepatic stellate cells
por: Kanmani, Paulraj, et al.
Publicado: (2022)

PGC-1α Suppresses the Activation of TGF-β/Smad Signaling via Targeting TGFβRI Downregulation by let-7b/c Upregulation
por: Choi, Hoon-In, et al.
Publicado: (2019)

Multiple plaque incisions with or without grafting for Peyronie's disease
por: Hegarty, Paul K., et al.
Publicado: (2022)

CCN5 attenuates profibrotic phenotypes of fibroblasts through the Smad6-CCN2 pathway: Potential role in epidural fibrosis
por: XU, HONGHAI, et al.
Publicado: (2015)

MicroRNA‑331 inhibits isoproterenol‑induced expression of profibrotic genes in cardiac myofibroblasts via the TGFβ/smad3 signaling pathway
por: Yousefi, Fatemeh, et al.
Publicado: (2021)

Sonographic patterns of Peyronie's disease in patients with absence of palpable plaques
por: Dell'Atti, Lucio, et al.
Publicado: (2018)

Corni Fructus Alleviates UUO-Induced Renal Fibrosis via TGF-β/Smad Signaling
por: Lee, Jin A., et al.
Publicado: (2022)

Suppression of Hepatic Epithelial-to-Mesenchymal Transition by Melittin via Blocking of TGFβ/Smad and MAPK-JNK Signaling Pathways
por: Park, Ji-Hyun, et al.
Publicado: (2017)

Anti-fibrotic Effects of Synthetic Oligodeoxynucleotide for TGF-β1 and Smad in an Animal Model of Liver Cirrhosis
por: Kim, Jung-Yeon, et al.
Publicado: (2017)

Urologists' Perceptions and Practice Patterns in Peyronie's Disease: A Korean Nationwide Survey Including Patient Satisfaction
por: Ko, Young Hwii, et al.
Publicado: (2014)

Ultrasound on Erect Penis Improves Plaque Identification in Patients With Peyronie’s Disease
por: Liu, Yu, et al.
Publicado: (2019)

Smad7-overexpressing rat BMSCs inhibit the fibrosis of hepatic stellate cells by regulating the TGF-β1/Smad signaling pathway
por: Wu, Shi-Pin, et al.
Publicado: (2017)

PPARδ Agonist GW501516 Suppresses the TGF-β-Induced Profibrotic Response of Human Bronchial Fibroblasts from Asthmatic Patients
por: Paw, Milena, et al.
Publicado: (2023)

TAZ contributes to pulmonary fibrosis by activating profibrotic functions of lung fibroblasts
por: Noguchi, Satoshi, et al.
Publicado: (2017)

Regulation of Cellular Senescence Is Independent from Profibrotic Fibroblast-Deposited ECM
por: Blokland, Kaj E. C., et al.
Publicado: (2021)

SETDB1 regulates SMAD7 expression for breast cancer metastasis
por: Ryu, Tae Young, et al.
Publicado: (2019)

Antifibrotic effects of eupatilin on TGF-β1-treated human vocal fold fibroblasts
por: Park, Sung Joon, et al.
Publicado: (2021)

The uPA System Differentially Alters Fibroblast Fate and Profibrotic Ability in Skin Fibrosis
por: Zou, Ming-Li, et al.
Publicado: (2022)

AB081. Effects of combination therapy of Tamoxifen, L-carnitine and daily PDE5 inhibitors in the Peyronie’s disease
por: Kang, Jae Il, et al.
Publicado: (2016)

TGF-β1-induced HSP47 regulates extracellular matrix accumulation via Smad2/3 signaling pathways in nasal fibroblasts
por: Kim, Hae-Ji, et al.
Publicado: (2019)

Examining Liver Cancer Patients and a High-Risk Group in a Vulnerable Area: An Experience from the Ulleung Liver Cancer Prevention and Management Project
por: Ryu, Dong-Hee, et al.
Publicado: (2020)

Review of the Surgical Approaches for Peyronie's Disease: Corporeal Plication and Plaque Incision with Grafting
por: Tran, Viet Q., et al.
Publicado: (2008)

Twenty Years of Plaque Incision and Grafting for Peyronie’s Disease: A Review of Literature
por: Rice, Patrick G., et al.
Publicado: (2019)

IL-17 Induced Stromal Cell–Derived Factor-1 and Profibrotic Factor in Keloid-Derived Skin Fibroblasts via the STAT3 Pathway
por: Lee, Seon-Yeong, et al.
Publicado: (2019)

Identification of the proliferative effect of Smad2 and 3 in the TGF β2/Smad signaling pathway using RNA interference in a glioma cell line
por: DONG, CHENGYUAN, et al.
Publicado: (2015)

AB084. intracavernous administration of embryonic stem cell-derived exosome restores erectile function through penile neurovascular regeneration in the streptozotocin-induced diabetic mouse
por: Kwon, Mi-Hye, et al.
Publicado: (2018)

AB088. Inhibition of prongf pathway restores erectile function through dual angiogenic and neurotrophic effects in the diabetic mouse
por: Minh, Nguyen Nhat, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_7o6ob926nsokgv7p5vbk3dej2f