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Role of the 5-HT(4) receptor in chronic fluoxetine treatment-induced neurogenic activity and granule cell dematuration in the dentate gyrus

BACKGROUND: Chronic treatment with selective serotonin (5-HT) reuptake inhibitors (SSRIs) facilitates adult neurogenesis and reverses the state of maturation in mature granule cells (GCs) in the dentate gyrus (DG) of the hippocampus. Recent studies have suggested that the 5-HT(4) receptor is involve...

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Detalles Bibliográficos
Autores principales: Imoto, Yuki, Kira, Toshihiko, Sukeno, Mamiko, Nishitani, Naoya, Nagayasu, Kazuki, Nakagawa, Takayuki, Kaneko, Shuji, Kobayashi, Katsunori, Segi-Nishida, Eri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430984/
https://www.ncbi.nlm.nih.gov/pubmed/25976618
http://dx.doi.org/10.1186/s13041-015-0120-3