X-shaped DNA potentiates therapeutic efficacy in colitis-associated colon cancer through dual activation of TLR9 and inflammasomes

BACKGROUND: Immunotherapy has been extensively pursed as a promising strategy for the treatment of cancer. Pattern-recognition receptors (PRRs) play important roles in triggering activation of innate and adaptive immunity. Therefore, agents that stimulate PRRs could be useful for cancer immunotherap...

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Detalles Bibliográficos
Autores principales: Koo, Jung Eun, Shin, Seung Won, Um, Soong Ho, Lee, Joo Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431032/
https://www.ncbi.nlm.nih.gov/pubmed/25971982
http://dx.doi.org/10.1186/s12943-015-0369-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431032/
https://www.ncbi.nlm.nih.gov/pubmed/25971982
http://dx.doi.org/10.1186/s12943-015-0369-2

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