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Rationally Designing Aptamer Sequences with Reduced Affinity for Controlled Sensor Performance
The relative ease of predicting the secondary structure of nucleic acid sequences lends itself to the design of sequences to perform desired functions. Here, we combine the utility of nucleic acid aptamers with predictable control over the secondary structure to rationally design sequences with cont...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431182/ https://www.ncbi.nlm.nih.gov/pubmed/25835184 http://dx.doi.org/10.3390/s150407754 |