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Rationally Designing Aptamer Sequences with Reduced Affinity for Controlled Sensor Performance

The relative ease of predicting the secondary structure of nucleic acid sequences lends itself to the design of sequences to perform desired functions. Here, we combine the utility of nucleic acid aptamers with predictable control over the secondary structure to rationally design sequences with cont...

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Detalles Bibliográficos
Autores principales: Schoukroun-Barnes, Lauren R., White, Ryan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431182/
https://www.ncbi.nlm.nih.gov/pubmed/25835184
http://dx.doi.org/10.3390/s150407754