A mRNA-Responsive G-Quadruplex-Based Drug Release System

G-quadruplex-based drug delivery carriers (GDDCs) were designed to capture and release a telomerase inhibitor in response to a target mRNA. Hybridization between a loop on the GDDC structure and the mRNA should cause the G-quadruplex structure of the GDDC to unfold and release the bound inhibitor, a...

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Detalles Bibliográficos
Autores principales: Yaku, Hidenobu, Murashima, Takashi, Miyoshi, Daisuke, Sugimoto, Naoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431183/
https://www.ncbi.nlm.nih.gov/pubmed/25905703
http://dx.doi.org/10.3390/s150409388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431183/
https://www.ncbi.nlm.nih.gov/pubmed/25905703
http://dx.doi.org/10.3390/s150409388

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