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Multivalent Aptamer/Gold Nanoparticle–Modified Graphene Oxide for Mass Spectrometry–Based Tumor Tissue Imaging

The protein mucin1 (MUC1) is an attractive target for cancer biomarkers because it is overexpressed in most adenocarcinomas. In this study, we exploited a MUC1-binding aptamer (Apt(MUC1)) as a targeting agent for nanoparticle-based imaging systems coupled with laser desorption/ionization mass spectr...

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Detalles Bibliográficos
Autores principales: Huang, Rong-Cing, Chiu, Wei-Jane, Po-Jung Lai, Irving, Huang, Chih-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431351/
https://www.ncbi.nlm.nih.gov/pubmed/25973571
http://dx.doi.org/10.1038/srep10292