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Orally active αvβ3 integrin inhibitor MK-0429 reduces melanoma metastasis

Melanoma remains one of the most aggressive types of cancer with a historically low survival rate. The αvβ3 integrin is involved in the progression of malignant melanoma. In the present study, the efficacy of MK-0429, a selective inhibitor of the αvβ3 integrin, was evaluated for its potential in the...

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Detalles Bibliográficos
Autores principales: PICKARSKI, MAUREEN, GLEASON, ALEXA, BEDNAR, BOHUMIL, DUONG, LE T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431436/
https://www.ncbi.nlm.nih.gov/pubmed/25872534
http://dx.doi.org/10.3892/or.2015.3910