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Orally active αvβ3 integrin inhibitor MK-0429 reduces melanoma metastasis
Melanoma remains one of the most aggressive types of cancer with a historically low survival rate. The αvβ3 integrin is involved in the progression of malignant melanoma. In the present study, the efficacy of MK-0429, a selective inhibitor of the αvβ3 integrin, was evaluated for its potential in the...
Autores principales: | PICKARSKI, MAUREEN, GLEASON, ALEXA, BEDNAR, BOHUMIL, DUONG, LE T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431436/ https://www.ncbi.nlm.nih.gov/pubmed/25872534 http://dx.doi.org/10.3892/or.2015.3910 |
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