Silibinin, a natural flavonoid, induces autophagy via ROS-dependent mitochondrial dysfunction and loss of ATP involving BNIP3 in human MCF7 breast cancer cells

Silibinin, derived from the milk thistle plant (Silybum marianum), has anticancer and chemopreventive properties. Silibinin has been reported to inhibit the growth of various types of cancer cells. However, the mechanisms by which silibinin exerts an anticancer effect are poorly defined. The present...

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Detalles Bibliográficos
Autores principales: JIANG, KAI, WANG, WEI, JIN, XIN, WANG, ZHAOYANG, JI, ZHIWEI, MENG, GUANMIN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431438/
https://www.ncbi.nlm.nih.gov/pubmed/25891311
http://dx.doi.org/10.3892/or.2015.3915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431438/
https://www.ncbi.nlm.nih.gov/pubmed/25891311
http://dx.doi.org/10.3892/or.2015.3915

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