Cargando…

Eprobe-mediated screening system for somatic mutations in the KRAS locus

Activating mutations in the Kirsten rat sarcoma viral oncogene homolog (KRAS) loci are largely predictive of resistance to epidermal growth factor receptor (EGFR) therapy in colorectal cancer (CRC). A highly sensitive detection system for the KRAS gene mutations is urgently needed; however, conventi...

Descripción completa

Detalles Bibliográficos
Autores principales: ATSUMI, JUN, HANAMI, TAKESHI, ENOKIDA, YASUAKI, OGAWA, HIROOMI, DELOBEL, DIANE, MITANI, YASUMASA, KIMURA, YASUMASA, SOMA, TAKAHIRO, TAGAMI, MICHIHIRA, TAKASE, YOSHIAKI, ICHIHARA, TATSUO, TAKEYOSHI, IZUMI, USUI, KENGO, HAYASHIZAKI, YOSHIHIDE, SHIMIZU, KIMIHIRO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431451/
https://www.ncbi.nlm.nih.gov/pubmed/25823645
http://dx.doi.org/10.3892/or.2015.3883