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Refractory cachexia is associated with increased plasma concentrations of fentanyl in cancer patients

BACKGROUND: An appropriate plasma concentration of fentanyl is the key to achieving good pain control in cancer patients. Cachexia, a multifactorial syndrome, is known to affect drug-metabolizing enzymes. However, the fentanyl concentrations in the blood of patients with cachexia have not been analy...

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Detalles Bibliográficos
Autores principales: Suno, Manabu, Endo, Yuriko, Nishie, Hiroyuki, Kajizono, Makoto, Sendo, Toshiaki, Matsuoka, Junji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431473/
https://www.ncbi.nlm.nih.gov/pubmed/26056457
http://dx.doi.org/10.2147/TCRM.S79374