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Delivery of a mucin domain enriched in cysteine residues strengthens the intestinal mucous barrier

A weakening of the gut mucous barrier permits an increase in the access of intestinal luminal contents to the epithelial cells, which will trigger the inflammatory response. In inflammatory bowel diseases, there is an inappropriate and ongoing activation of the immune system, possibly because the in...

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Detalles Bibliográficos
Autores principales: Gouyer, Valérie, Dubuquoy, Laurent, Robbe-Masselot, Catherine, Neut, Christel, Singer, Elisabeth, Plet, Ségolène, Geboes, Karel, Desreumaux, Pierre, Gottrand, Frédéric, Desseyn, Jean-Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431476/
https://www.ncbi.nlm.nih.gov/pubmed/25974250
http://dx.doi.org/10.1038/srep09577