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Delivery of a mucin domain enriched in cysteine residues strengthens the intestinal mucous barrier
A weakening of the gut mucous barrier permits an increase in the access of intestinal luminal contents to the epithelial cells, which will trigger the inflammatory response. In inflammatory bowel diseases, there is an inappropriate and ongoing activation of the immune system, possibly because the in...
Autores principales: | Gouyer, Valérie, Dubuquoy, Laurent, Robbe-Masselot, Catherine, Neut, Christel, Singer, Elisabeth, Plet, Ségolène, Geboes, Karel, Desreumaux, Pierre, Gottrand, Frédéric, Desseyn, Jean-Luc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431476/ https://www.ncbi.nlm.nih.gov/pubmed/25974250 http://dx.doi.org/10.1038/srep09577 |
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