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Loss of LKB1 disrupts breast epithelial cell polarity and promotes breast cancer metastasis and invasion
BACKGROUND: LKB1, also known as STK11, is a master kinase that serves as an energy metabolic sensor and is involved in cell polarity regulation. Recent studies have indicated that LKB1 is related to breast tumorigenesis and breast cancer progression. However, little work has been done on the roles o...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431490/ https://www.ncbi.nlm.nih.gov/pubmed/25178656 http://dx.doi.org/10.1186/s13046-014-0070-0 |