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Loss of LKB1 disrupts breast epithelial cell polarity and promotes breast cancer metastasis and invasion

BACKGROUND: LKB1, also known as STK11, is a master kinase that serves as an energy metabolic sensor and is involved in cell polarity regulation. Recent studies have indicated that LKB1 is related to breast tumorigenesis and breast cancer progression. However, little work has been done on the roles o...

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Detalles Bibliográficos
Autores principales:	Li, Juan, Liu, Jie, Li, Pingping, Mao, Xiaona, Li, Wenjie, Yang, Jin, Liu, Peijun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431490/ https://www.ncbi.nlm.nih.gov/pubmed/25178656 http://dx.doi.org/10.1186/s13046-014-0070-0

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