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Genome-wide RNAi screen for synthetic lethal interactions with the C. elegans kinesin-5 homolog BMK-1

Kinesins are a superfamily of microtubule-based molecular motors that perform various transport needs and have essential roles in cell division. Among these, the kinesin-5 family has been shown to play a major role in the formation and maintenance of the bipolar mitotic spindle. Moreover, recent wor...

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Detalles Bibliográficos
Autores principales: Maia, André F., Tanenbaum, Marvin E., Galli, Matilde, Lelieveld, Daphne, Egan, David A., Gassmann, Reto, Sunkel, Claudio E., van den Heuvel, Sander, Medema, René H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431526/
https://www.ncbi.nlm.nih.gov/pubmed/25984351
http://dx.doi.org/10.1038/sdata.2015.20