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Genome-wide RNAi screen for synthetic lethal interactions with the C. elegans kinesin-5 homolog BMK-1
Kinesins are a superfamily of microtubule-based molecular motors that perform various transport needs and have essential roles in cell division. Among these, the kinesin-5 family has been shown to play a major role in the formation and maintenance of the bipolar mitotic spindle. Moreover, recent wor...
Autores principales: | Maia, André F., Tanenbaum, Marvin E., Galli, Matilde, Lelieveld, Daphne, Egan, David A., Gassmann, Reto, Sunkel, Claudio E., van den Heuvel, Sander, Medema, René H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431526/ https://www.ncbi.nlm.nih.gov/pubmed/25984351 http://dx.doi.org/10.1038/sdata.2015.20 |
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