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Neddylation Promotes Ubiquitylation and Release of Ku from DNA-Damage Sites

The activities of many DNA-repair proteins are controlled through reversible covalent modification by ubiquitin and ubiquitin-like molecules. Nonhomologous end-joining (NHEJ) is the predominant DNA double-strand break (DSB) repair pathway in mammalian cells and is initiated by DSB ends being recogni...

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Detalles Bibliográficos
Autores principales:	Brown, Jessica S., Lukashchuk, Natalia, Sczaniecka-Clift, Matylda, Britton, Sébastien, le Sage, Carlos, Calsou, Patrick, Beli, Petra, Galanty, Yaron, Jackson, Stephen P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431666/ https://www.ncbi.nlm.nih.gov/pubmed/25921528 http://dx.doi.org/10.1016/j.celrep.2015.03.058

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