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Architecture of the Ubiquitylation Module of the Yeast Ccr4-Not Complex
The Ccr4-Not complex regulates eukaryotic gene expression at multiple levels, including mRNA turnover, translational repression, and transcription. We have studied the ubiquitylation module of the yeast Ccr4-Not complex and addressed how E3 ligase binds cognate E2 and how it is tethered to the compl...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431670/ https://www.ncbi.nlm.nih.gov/pubmed/25914052 http://dx.doi.org/10.1016/j.str.2015.03.011 |