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Architecture of the Ubiquitylation Module of the Yeast Ccr4-Not Complex

The Ccr4-Not complex regulates eukaryotic gene expression at multiple levels, including mRNA turnover, translational repression, and transcription. We have studied the ubiquitylation module of the yeast Ccr4-Not complex and addressed how E3 ligase binds cognate E2 and how it is tethered to the compl...

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Detalles Bibliográficos
Autores principales: Bhaskar, Varun, Basquin, Jérôme, Conti, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431670/
https://www.ncbi.nlm.nih.gov/pubmed/25914052
http://dx.doi.org/10.1016/j.str.2015.03.011