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Autoselection of Cytoplasmic Yeast Virus Like Elements Encoding Toxin/Antitoxin Systems Involves a Nuclear Barrier for Immunity Gene Expression

Cytoplasmic virus like elements (VLEs) from Kluyveromyces lactis (Kl), Pichia acaciae (Pa) and Debaryomyces robertsiae (Dr) are extremely A/T-rich (>75%) and encode toxic anticodon nucleases (ACNases) along with specific immunity proteins. Here we show that nuclear, not cytoplasmic expression of...

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Detalles Bibliográficos
Autores principales: Kast, Alene, Voges, Raphael, Schroth, Michael, Schaffrath, Raffael, Klassen, Roland, Meinhardt, Friedhelm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431711/
https://www.ncbi.nlm.nih.gov/pubmed/25973601
http://dx.doi.org/10.1371/journal.pgen.1005005