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55P0110, a Novel Synthetic Compound Developed from a Plant Derived Backbone Structure, Shows Promising Anti-Hyperglycaemic Activity in Mice

Starting off with a structure derived from the natural compound multiflorine, a derivatisation program aimed at the discovery and initial characterisation of novel compounds with antidiabetic potential. Design and discovery of the structures was guided by oral bioactivities obtained in oral glucose...

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Detalles Bibliográficos
Autores principales: Brunmair, Barbara, Lehner, Zsuzsanna, Stadlbauer, Karin, Adorjan, Immanuel, Frobel, Klaus, Scherer, Thomas, Luger, Anton, Bauer, Leonhardt, Fürnsinn, Clemens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431753/
https://www.ncbi.nlm.nih.gov/pubmed/25973898
http://dx.doi.org/10.1371/journal.pone.0126847