Inhibition and Reversal of Microbial Attachment by an Antibody with Parasteric Activity against the FimH Adhesin of Uropathogenic E. coli

Attachment proteins from the surface of eukaryotic cells, bacteria and viruses are critical receptors in cell adhesion or signaling and are primary targets for the development of vaccines and therapeutic antibodies. It is proposed that the ligand-binding pocket in receptor proteins can shift between...

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Detalles Bibliográficos
Autores principales: Kisiela, Dagmara I., Avagyan, Hovhannes, Friend, Della, Jalan, Aachal, Gupta, Shivani, Interlandi, Gianluca, Liu, Yan, Tchesnokova, Veronika, Rodriguez, Victoria B., Sumida, John P., Strong, Roland K., Wu, Xue-Ru, Thomas, Wendy E., Sokurenko, Evgeni V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431754/
https://www.ncbi.nlm.nih.gov/pubmed/25974133
http://dx.doi.org/10.1371/journal.ppat.1004857

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431754/
https://www.ncbi.nlm.nih.gov/pubmed/25974133
http://dx.doi.org/10.1371/journal.ppat.1004857

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