The 4E-BP Caf20p Mediates Both eIF4E-Dependent and Independent Repression of Translation

Translation initiation factor eIF4E mediates mRNA selection for protein synthesis via the mRNA 5’cap. A family of binding proteins, termed the 4E-BPs, interact with eIF4E to hinder ribosome recruitment. Mechanisms underlying mRNA specificity for 4E-BP control remain poorly understood. Saccharomyces...

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Detalles Bibliográficos
Autores principales: Castelli, Lydia M., Talavera, David, Kershaw, Christopher J., Mohammad-Qureshi, Sarah S., Costello, Joseph L., Rowe, William, Sims, Paul F. G., Grant, Christopher M., Hubbard, Simon J., Ashe, Mark P., Pavitt, Graham D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431810/
https://www.ncbi.nlm.nih.gov/pubmed/25973932
http://dx.doi.org/10.1371/journal.pgen.1005233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431810/
https://www.ncbi.nlm.nih.gov/pubmed/25973932
http://dx.doi.org/10.1371/journal.pgen.1005233

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