Brucella spp. Lumazine Synthase Induces a TLR4-Mediated Protective Response against B16 Melanoma in Mice

Brucella Lumazine Synthase (BLS) is a highly immunogenic decameric protein which can accept the fusion of foreign proteins at its ten N-termini. These chimeras are very efficient to elicit systemic and oral immunity without adjuvants. BLS signaling via Toll-Like Receptor 4 (TLR4) regulates innate an...

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Detalles Bibliográficos
Autores principales: Rossi, Andrés H., Farias, Ana, Fernández, Javier E., Bonomi, Hernán R., Goldbaum, Fernando A., Berguer, Paula M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431812/
https://www.ncbi.nlm.nih.gov/pubmed/25973756
http://dx.doi.org/10.1371/journal.pone.0126827

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431812/
https://www.ncbi.nlm.nih.gov/pubmed/25973756
http://dx.doi.org/10.1371/journal.pone.0126827

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