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Identification of Sestrin3 Involved in the In vitro Resistance of Colorectal Cancer Cells to Irinotecan
Irinotecan, an analogue of camptothecin, is frequently used as a single agent or in combination with other anticancer drugs for the treatment of colorectal cancer. However, the drug resistance of tumors is a major obstacle to successful cancer treatment. In this study, we established that cells acqu...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431826/ https://www.ncbi.nlm.nih.gov/pubmed/25973791 http://dx.doi.org/10.1371/journal.pone.0126830 |