Acid sphingomyelinase inhibition protects mice from lung edema and lethal Staphylococcus aureus sepsis

ABSTRACT: Pulmonary edema associated with increased vascular permeability is a severe complication of Staphylococcus aureus–induced sepsis and an important cause of human pathology and death. We investigated the role of the mammalian acid sphingomyelinase (Asm)/ceramide system in the development of...

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Detalles Bibliográficos
Autores principales: Peng, Huiming, Li, Cao, Kadow, Stephanie, Henry, Brian D., Steinmann, Jörg, Becker, Katrin Anne, Riehle, Andrea, Beckmann, Natalie, Wilker, Barbara, Li, Pin-Lan, Pritts, Timothy, Edwards, Michael J., Zhang, Yang, Gulbins, Erich, Grassmé, Heike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432103/
https://www.ncbi.nlm.nih.gov/pubmed/25616357
http://dx.doi.org/10.1007/s00109-014-1246-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432103/
https://www.ncbi.nlm.nih.gov/pubmed/25616357
http://dx.doi.org/10.1007/s00109-014-1246-y

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