Development and application of an aggregate adherence metric derived from population pharmacokinetics to inform clinical trial enrichment

Nonadherence to prescribed medication is a common barrier to effective treatment, and current options to determine adherence are limited. This study describes development of an aggregate adherence measure based on population pharmacokinetics (PK), and its comparison to a subjective questionnaire, th...

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Detalles Bibliográficos
Autores principales: Knights, Jonathan, Rohatagi, Shashank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432109/
https://www.ncbi.nlm.nih.gov/pubmed/25821065
http://dx.doi.org/10.1007/s10928-015-9414-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432109/
https://www.ncbi.nlm.nih.gov/pubmed/25821065
http://dx.doi.org/10.1007/s10928-015-9414-4

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