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Development and application of an aggregate adherence metric derived from population pharmacokinetics to inform clinical trial enrichment
Nonadherence to prescribed medication is a common barrier to effective treatment, and current options to determine adherence are limited. This study describes development of an aggregate adherence measure based on population pharmacokinetics (PK), and its comparison to a subjective questionnaire, th...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432109/ https://www.ncbi.nlm.nih.gov/pubmed/25821065 http://dx.doi.org/10.1007/s10928-015-9414-4 |