The small GTPase Arl8b regulates assembly of the mammalian HOPS complex on lysosomes

The homotypic fusion and protein sorting (HOPS) complex is a multi-subunit complex conserved from yeast to mammals that regulates late endosome and lysosome fusion. However, little is known about how the HOPS complex is recruited to lysosomes in mammalian cells. Here, we report that the small GTPase...

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Detalles Bibliográficos
Autores principales: Khatter, Divya, Raina, Vivek B., Dwivedi, Devashish, Sindhwani, Aastha, Bahl, Surbhi, Sharma, Mahak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432227/
https://www.ncbi.nlm.nih.gov/pubmed/25908847
http://dx.doi.org/10.1242/jcs.162651

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432227/
https://www.ncbi.nlm.nih.gov/pubmed/25908847
http://dx.doi.org/10.1242/jcs.162651

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