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Lineage specific evolution of the VNTR composite retrotransposon central domain and its role in retrotransposition of gibbon LAVA elements

BACKGROUND: VNTR (Variable Number of Tandem Repeats) composite retrotransposons - SVA (SINE-R-VNTR-Alu), LAVA (LINE-1-Alu-VNTR-Alu), PVA (PTGR2-VNTR-Alu) and FVA (FRAM-VNTR-Alu) - are specific to hominoid primates. Their assembly, the evolution of their 5’ and 3’ domains, and the functional signific...

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Detalles Bibliográficos
Autores principales: Lupan, Iulia, Bulzu, Paul, Popescu, Octavian, Damert, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432496/
https://www.ncbi.nlm.nih.gov/pubmed/25981446
http://dx.doi.org/10.1186/s12864-015-1543-z