Occupancy by key transcription factors is a more accurate predictor of enhancer activity than histone modifications or chromatin accessibility

BACKGROUND: Regulated gene expression controls organismal development, and variation in regulatory patterns has been implicated in complex traits. Thus accurate prediction of enhancers is important for further understanding of these processes. Genome-wide measurement of epigenetic features, such as...

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Detalles Bibliográficos
Autores principales: Dogan, Nergiz, Wu, Weisheng, Morrissey, Christapher S, Chen, Kuan-Bei, Stonestrom, Aaron, Long, Maria, Keller, Cheryl A, Cheng, Yong, Jain, Deepti, Visel, Axel, Pennacchio, Len A, Weiss, Mitchell J, Blobel, Gerd A, Hardison, Ross C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432502/
https://www.ncbi.nlm.nih.gov/pubmed/25984238
http://dx.doi.org/10.1186/s13072-015-0009-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432502/
https://www.ncbi.nlm.nih.gov/pubmed/25984238
http://dx.doi.org/10.1186/s13072-015-0009-5

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