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Evaluating information content of SNPs for sample-tagging in re-sequencing projects

Sample-tagging is designed for identification of accidental sample mix-up, which is a major issue in re-sequencing studies. In this work, we develop a model to measure the information content of SNPs, so that we can optimize a panel of SNPs that approach the maximal information for discrimination. T...

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Detalles Bibliográficos
Autores principales: Hu, Hao, Liu, Xiang, Jin, Wenfei, Hilger Ropers, H, Wienker, Thomas F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432563/
https://www.ncbi.nlm.nih.gov/pubmed/25975447
http://dx.doi.org/10.1038/srep10247