Non-autonomous DAF-16/FOXO activity antagonizes age-related loss of C. elegans germline stem/progenitor cells

Stem cells maintain tissues and organs over the lifespan of individuals. How aging influences this process is unclear. Here we investigate the effects of aging on C. elegans germline stem/progenitor cells and show that the progenitor pool is depleted over time in a manner dependent on inhibition of...

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Detalles Bibliográficos
Autores principales: Qin, Zhao, Hubbard, E. Jane Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432587/
https://www.ncbi.nlm.nih.gov/pubmed/25960195
http://dx.doi.org/10.1038/ncomms8107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432587/
https://www.ncbi.nlm.nih.gov/pubmed/25960195
http://dx.doi.org/10.1038/ncomms8107

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