Phosphoproteomic Analysis of Cell-Based Resistance to BRAF Inhibitor Therapy in Melanoma

The treatment of melanoma by targeted inhibition of the mutated kinase BRAF with small molecules only temporarily suppresses metastatic disease. In the face of chemical inhibition tumor plasticity, both innate and adaptive, promotes survival through the biochemical and genetic reconfiguration of cel...

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Detalles Bibliográficos
Autores principales: Parker, Robert, Vella, Laura J., Xavier, Dylan, Amirkhani, Ardeshir, Parker, Jimmy, Cebon, Jonathan, Molloy, Mark P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432663/
https://www.ncbi.nlm.nih.gov/pubmed/26029660
http://dx.doi.org/10.3389/fonc.2015.00095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432663/
https://www.ncbi.nlm.nih.gov/pubmed/26029660
http://dx.doi.org/10.3389/fonc.2015.00095

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