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ISO-66, a novel inhibitor of macrophage migration inhibitory factor, shows efficacy in melanoma and colon cancer models

Macrophage migration inhibitory factor (MIF) is a pleiotropic pro-inflammatory cytokine, which possesses a contributing role in cancer progression and metastasis and, thus, is now considered a promising anticancer drug target. Many MIF-inactivating strategies have proven successful in delaying cance...

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Detalles Bibliográficos
Autores principales: IOANOU, KYRIAKI, CHENG, KAI FAN, CRICH LOW, GREGG V., BIRMPILIS, ANASTASIOS I., LO LIS, ELIAS J., TSITSILONIS, OURANIA E., AL-ABED, YOUSEF
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432716/
https://www.ncbi.nlm.nih.gov/pubmed/25050663
http://dx.doi.org/10.3892/ijo.2014.2551