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The cis and trans effects of the risk variants of coronary artery disease in the Chr9p21 region

BACKGROUND: Recent genome-wide association studies (GWAS) have shown that single nucleotide polymorphisms (SNPs) in the Chr9p21 region are associated with coronary artery disease (CAD). Most of the SNPs identified in this region are non-coding SNPs, suggesting that they may influence gene expression...

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Detalles Bibliográficos
Autores principales: Zhao, Wei, Smith, Jennifer A, Mao, Guangmei, Fornage, Myriam, Peyser, Patricia A, Sun, Yan V, Turner, Stephen T, Kardia, Sharon LR
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432789/
https://www.ncbi.nlm.nih.gov/pubmed/25958224
http://dx.doi.org/10.1186/s12920-015-0094-0