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The methyl binding domain 3/nucleosome remodelling and deacetylase complex regulates neural cell fate determination and terminal differentiation in the cerebral cortex

BACKGROUND: Chromatin-modifying complexes have key roles in regulating various aspects of neural stem cell biology, including self-renewal and neurogenesis. The methyl binding domain 3/nucleosome remodelling and deacetylation (MBD3/NuRD) co-repressor complex facilitates lineage commitment of pluripo...

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Detalles Bibliográficos
Autores principales: Knock, Erin, Pereira, João, Lombard, Patrick D, Dimond, Andrew, Leaford, Donna, Livesey, Frederick J, Hendrich, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432814/
https://www.ncbi.nlm.nih.gov/pubmed/25934499
http://dx.doi.org/10.1186/s13064-015-0040-z