Lenalidomide reduces microglial activation and behavioral deficits in a transgenic model of Parkinson’s disease

BACKGROUND: Parkinson’s disease (PD) is one of the most common causes of dementia and motor deficits in the elderly. PD is characterized by the abnormal accumulation of the synaptic protein alpha-synuclein (α-syn) and degeneration of dopaminergic neurons in substantia nigra, which leads to neurodege...

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Detalles Bibliográficos
Autores principales: Valera, Elvira, Mante, Michael, Anderson, Scott, Rockenstein, Edward, Masliah, Eliezer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432827/
https://www.ncbi.nlm.nih.gov/pubmed/25966683
http://dx.doi.org/10.1186/s12974-015-0320-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432827/
https://www.ncbi.nlm.nih.gov/pubmed/25966683
http://dx.doi.org/10.1186/s12974-015-0320-x

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