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Lenalidomide reduces microglial activation and behavioral deficits in a transgenic model of Parkinson’s disease
BACKGROUND: Parkinson’s disease (PD) is one of the most common causes of dementia and motor deficits in the elderly. PD is characterized by the abnormal accumulation of the synaptic protein alpha-synuclein (α-syn) and degeneration of dopaminergic neurons in substantia nigra, which leads to neurodege...
Autores principales: | Valera, Elvira, Mante, Michael, Anderson, Scott, Rockenstein, Edward, Masliah, Eliezer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432827/ https://www.ncbi.nlm.nih.gov/pubmed/25966683 http://dx.doi.org/10.1186/s12974-015-0320-x |
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