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Epigenetic repression of Krüppel-like factor 4 through Dnmt1 contributes to EMT in renal fibrosis

Krüppel-like factor 4 (KLF4) is a transcription factor which plays divergent roles in a number of physiological or pathological process. However, the expression and role of KLF4 in renal fibrosis remain undetermined. The aim of the present study was to determine the epigenetic alterations of KLF4 an...

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Detalles Bibliográficos
Autores principales: XIAO, XIANGCHENG, TANG, WENBIN, YUAN, QIONGJING, PENG, LING, YU, PINGPING
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432929/
https://www.ncbi.nlm.nih.gov/pubmed/25892014
http://dx.doi.org/10.3892/ijmm.2015.2189