Apolipoprotein E-dependent load of white matter hyperintensities in Alzheimer’s disease: a voxel-based lesion mapping study

INTRODUCTION: White matter (WM) magnetic resonance imaging (MRI) hyperintensities are common in Alzheimer’s disease (AD), but their pathophysiological relevance and relationship to genetic factors are unclear. In the present study, we investigated potential apolipoprotein E (APOE)-dependent effects...

Descripción completa

Detalles Bibliográficos
Autores principales: Morgen, Katrin, Schneider, Michael, Frölich, Lutz, Tost, Heike, Plichta, Michael M, Kölsch, Heike, Rakebrandt, Fabian, Rienhoff, Otto, Jessen, Frank, Peters, Oliver, Jahn, Holger, Luckhaus, Christian, Hüll, Michael, Gertz, Hermann-Josef, Schröder, Johannes, Hampel, Harald, Teipel, Stefan J, Pantel, Johannes, Heuser, Isabella, Wiltfang, Jens, Rüther, Eckart, Kornhuber, Johannes, Maier, Wolfgang, Meyer-Lindenberg, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432954/
https://www.ncbi.nlm.nih.gov/pubmed/25984242
http://dx.doi.org/10.1186/s13195-015-0111-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432954/
https://www.ncbi.nlm.nih.gov/pubmed/25984242
http://dx.doi.org/10.1186/s13195-015-0111-8

Ejemplares similares