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Stimulus-dependent differences in signalling regulate epithelial-mesenchymal plasticity and change the effects of drugs in breast cancer cell lines

INTRODUCTION: The normal process of epithelial mesenchymal transition (EMT) is subverted by carcinoma cells to facilitate metastatic spread. Cancer cells rarely undergo a full conversion to the mesenchymal phenotype, and instead adopt positions along the epithelial-mesenchymal axis, a propensity we...

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Detalles Bibliográficos
Autores principales: Cursons, Joseph, Leuchowius, Karl-Johan, Waltham, Mark, Tomaskovic-Crook, Eva, Foroutan, Momeneh, Bracken, Cameron P, Redfern, Andrew, Crampin, Edmund J, Street, Ian, Davis, Melissa J, Thompson, Erik W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432969/
https://www.ncbi.nlm.nih.gov/pubmed/25975820
http://dx.doi.org/10.1186/s12964-015-0106-x