HaploShare: identification of extended haplotypes shared by cases and evaluation against controls

Recent founder mutations may play important roles in complex diseases and Mendelian disorders. Detecting shared haplotypes that are identical by descent (IBD) could facilitate discovery of these mutations. Several programs address this, but are usually limited to detecting pair-wise shared haplotype...

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Detalles Bibliográficos
Autores principales: Ying, Dingge, Sham, Pak Chung, Smith, David Keith, Zhang, Lu, Lau, Yu Lung, Yang, Wanling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432975/
https://www.ncbi.nlm.nih.gov/pubmed/25956955
http://dx.doi.org/10.1186/s13059-015-0662-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432975/
https://www.ncbi.nlm.nih.gov/pubmed/25956955
http://dx.doi.org/10.1186/s13059-015-0662-9

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