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Applications of CRISPR-Cas9 mediated genome engineering
Targeted mutagenesis based on homologous recombination has been a powerful tool for understanding the mechanisms underlying development, normal physiology, and disease. A recent breakthrough in genome engineering technology based on the class of RNA-guided endonucleases, such as clustered regularly...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433013/ https://www.ncbi.nlm.nih.gov/pubmed/25984354 http://dx.doi.org/10.1186/s40779-015-0038-1 |