A multi-SNP association test for complex diseases incorporating an optimal P-value threshold algorithm in nuclear families

BACKGROUND: Genome-wide association studies (GWAS) have become a common approach to identifying single nucleotide polymorphisms (SNPs) associated with complex diseases. As complex diseases are caused by the joint effects of multiple genes, while the effect of individual gene or SNP is modest, a meth...

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Detalles Bibliográficos
Autores principales: Wang, Yi-Ting, Sung, Pei-Yuan, Lin, Peng-Lin, Yu, Ya-Wen, Chung, Ren-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433014/
https://www.ncbi.nlm.nih.gov/pubmed/25975968
http://dx.doi.org/10.1186/s12864-015-1620-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433014/
https://www.ncbi.nlm.nih.gov/pubmed/25975968
http://dx.doi.org/10.1186/s12864-015-1620-3

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