The truth about metagenomics: quantifying and counteracting bias in 16S rRNA studies

BACKGROUND: Characterizing microbial communities via next-generation sequencing is subject to a number of pitfalls involving sample processing. The observed community composition can be a severe distortion of the quantities of bacteria actually present in the microbiome, hampering analysis and threa...

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Detalles Bibliográficos
Autores principales: Brooks, J Paul, Edwards, David J, Harwich, Michael D, Rivera, Maria C, Fettweis, Jennifer M, Serrano, Myrna G, Reris, Robert A, Sheth, Nihar U, Huang, Bernice, Girerd, Philippe, Strauss, Jerome F, Jefferson, Kimberly K, Buck, Gregory A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433096/
https://www.ncbi.nlm.nih.gov/pubmed/25880246
http://dx.doi.org/10.1186/s12866-015-0351-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433096/
https://www.ncbi.nlm.nih.gov/pubmed/25880246
http://dx.doi.org/10.1186/s12866-015-0351-6

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