Synthesis and Characterization of a New Peptide Prodrug of Glucosamine with Enhanced Gut Permeability

The aim of this study was to synthesize a peptide prodrug of glucosamine (GlcN) with increased gut permeability through the gut peptide transporter 1 (PepT1). Glycine-Valine ester derivative of GlcN (GVG) was synthesised using solid phase synthesis followed by characterization and evaluation of its...

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Detalles Bibliográficos
Autores principales: Gilzad Kohan, Hamed, Kaur, Kamaljit, Jamali, Fakhreddin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433102/
https://www.ncbi.nlm.nih.gov/pubmed/25978315
http://dx.doi.org/10.1371/journal.pone.0126786

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433102/
https://www.ncbi.nlm.nih.gov/pubmed/25978315
http://dx.doi.org/10.1371/journal.pone.0126786

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